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Selective L-Nitroargininylaminopyrrolidine and L-Nitroargininylaminopiperidine Neuronal Nitric Oxide Synthase Inhibitors

Selective inhibition of the localized excess production of NO by neuronal nitric oxide synthase (nNOS) has been targeted as a potential means of treating various neurological disorders. Based on observations from the X-ray crystal structures of complexes of nNOS with two nNOS-selective inhibitors, (...

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Hlavní autoři: Seo, Jiwon, Martásek, Pavel, Roman, Linda J., Silverman, Richard B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1853295/
https://ncbi.nlm.nih.gov/pubmed/17239601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2007.01.001
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