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Hydroxyethylene Isosteres of Selective Neuronal Nitric Oxide Synthase Inhibitors

Nitric oxide (NO) is an important second messenger molecule for blood pressure homeostasis, as a neurotransmitter, and in the immune defense system. Excessive NO can lead to neurodegeneration and connective tissue damage. Three different isozymes of the enzyme nitric oxide synthase regulate NO produ...

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Autores principales: Erdal, Erik P., Martásek, Pavel, Roman, Linda J., Silverman, Richard B.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2001161/
https://ncbi.nlm.nih.gov/pubmed/17614291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2007.06.038
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