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Lactose Permease H(+)-Lactose Symporter: Mechanical Switch or Brownian Ratchet?
Lactose permease structure is deemed consistent with a mechanical switch device for H(+)-coupled symport. Because the crystallography-assigned docking position of thiodigalactoside (TDG) does not make close contact with several amino acids essential for symport; the switch model requires allosteric...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Biophysical Society
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1853157/ https://ncbi.nlm.nih.gov/pubmed/17325012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.100669 |
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