Progressive Neurodegeneration in Aspartylglycosaminuria Mice

Aspartylglycosaminuria (AGU) is one of the most common lysosomal storage disorders in humans. A mouse model for AGU has been recently generated through targeted disruption of the glycosylasparaginase gene, and at a young age the glycosyl asparaginase-deficient mice demonstrated many pathological cha...

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Main Authors: Gonzalez-Gomez, Ignacio, Mononen, Ilkka, Heisterkamp, Nora, Groffen, John, Kaartinen, Vesa
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 1998
Teme:
Animal Model
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1853058/
https://ncbi.nlm.nih.gov/pubmed/9777961
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