Mitochondrial respiration scavenges extramitochondrial superoxide anion via a nonenzymatic mechanism.

We determined that mitochondrial respiration reduced cytosolic oxidant stress in vivo and scavenged extramitochondrial superoxide anion (O2-.) in vitro. First, Saccharomyces cerevisiae deficient in both the cytosolic antioxidant cupro-zinc superoxide dismutase (Cu,Zn-SOD) and electron transport (Rho...

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Détails bibliographiques
Auteurs principaux: Guidot, D M, Repine, J E, Kitlowski, A D, Flores, S C, Nelson, S K, Wright, R M, McCord, J M
Format: Artigo
Langue:Inglês
Publié: 1995
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC185303/
https://ncbi.nlm.nih.gov/pubmed/7635949
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