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Distinct C/EBPα motifs regulate lipogenic and gluconeogenic gene expression in vivo
The C/EBPα transcription factor regulates hepatic nitrogen, glucose, lipid and iron metabolism. However, how it is able to independently control these processes is not known. Here, we use mouse knock-in mutagenesis to identify C/EBPα domains that specifically regulate hepatic gluconeogenesis and lip...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1852842/ https://ncbi.nlm.nih.gov/pubmed/17290224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601563 |
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