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XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gaps
XRCC4 and DNA ligase IV form a complex that is essential for the repair of all double-strand DNA breaks by the nonhomologous DNA end joining pathway in eukaryotes. We find here that human XRCC4:DNA ligase IV can ligate two double-strand DNA ends that have fully incompatible short 3′ overhang configu...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1852838/ https://ncbi.nlm.nih.gov/pubmed/17290226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601559 |
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