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An essential role of KREPB4 in RNA editing and structural integrity of the editosome in Trypanosoma brucei
RNA editing in the sleeping sickness parasite Trypanosoma brucei remodels mitochondrial transcripts by the addition and deletion of uridylates as specified by guide RNAs. Editing is catalyzed by at least three distinct ∼20S multiprotein editosomes, all of which contain KREPB4, a protein with RNase I...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1852822/ https://ncbi.nlm.nih.gov/pubmed/17369311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.327707 |
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