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Mutational analysis of Trypanosoma brucei editosome proteins KREPB4 and KREPB5 reveals domains critical for function

The transcriptome of kinetoplastid mitochondria undergoes extensive RNA editing that inserts and deletes uridine residues (U's) to produce mature mRNAs. The editosome is a multiprotein complex that provides endonuclease, TUTase, exonuclease, and ligase activities required for RNA editing. The e...

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Main Authors: Carnes, Jason, Schnaufer, Achim, McDermott, Suzanne M., Domingo, Gonzalo, Proff, Rose, Steinberg, Alodie G., Kurtz, Irina, Stuart, Kenneth
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446712/
https://ncbi.nlm.nih.gov/pubmed/22919050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.035048.112
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