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An essential role of KREPB4 in RNA editing and structural integrity of the editosome in Trypanosoma brucei

RNA editing in the sleeping sickness parasite Trypanosoma brucei remodels mitochondrial transcripts by the addition and deletion of uridylates as specified by guide RNAs. Editing is catalyzed by at least three distinct ∼20S multiprotein editosomes, all of which contain KREPB4, a protein with RNase I...

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Detalhes bibliográficos
Main Authors: Babbarwal, Vinod Kumar, Fleck, Michele, Ernst, Nancy Lewis, Schnaufer, Achim, Stuart, Kenneth
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852822/
https://ncbi.nlm.nih.gov/pubmed/17369311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.327707
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