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Genomic instability of the host cell induced by the human papillomavirus replication machinery

Development of invasive cervical cancer upon infection by ‘high-risk' human papillomavirus (HPV) in humans is a stepwise process in which some of the initially episomal ‘high-risk' type of HPVs (HR-HPVs) integrate randomly into the host cell genome. We show that HPV replication proteins E1...

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Autores principales: Kadaja, Meelis, Sumerina, Alina, Verst, Tatjana, Ojarand, Mari, Ustav, Ene, Ustav, Mart
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852791/
https://ncbi.nlm.nih.gov/pubmed/17396148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601665
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