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Reconstruction of a pathway of antigen processing and class II MHC peptide capture

Endocytosed antigens are proteolytically processed and small amounts of peptides captured by class II MHC molecules. The details of antigen proteolysis, peptide capture and how destruction of T-cell epitopes is avoided are incompletely understood. Using the tetanus toxin antigen, we show that the in...

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Bibliografske podrobnosti
Main Authors: Moss, Catherine X, Tree, Timothy I, Watts, Colin
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852786/
https://ncbi.nlm.nih.gov/pubmed/17396153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601660
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