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Reconstruction of a pathway of antigen processing and class II MHC peptide capture
Endocytosed antigens are proteolytically processed and small amounts of peptides captured by class II MHC molecules. The details of antigen proteolysis, peptide capture and how destruction of T-cell epitopes is avoided are incompletely understood. Using the tetanus toxin antigen, we show that the in...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
2007
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1852786/ https://ncbi.nlm.nih.gov/pubmed/17396153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601660 |
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