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HEXOSE 6-PHOSPHATE DEHYDROGENASE (H6PD) AND CORTICOSTEROID METABOLISM
Cortisone or (in rodents) 11-dehydrocorticosterone are reduced to cortisol or corticosterone, respectively, by the oxo-reductase activity of 11β-hydroxysteroid dehydrogenase type 1(11-HSD1). This requires NADPH, generated by hexose-6-phosphate dehydrogenase (H6PD), a component of the pentose phospha...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1852482/ https://ncbi.nlm.nih.gov/pubmed/17240046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2006.12.022 |
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