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Crystallographic and Mutational Studies of Mycobacterium tuberculosis recA Mini-Inteins Suggest a Pivotal Role for a Highly Conserved Aspartate Residue

The 440-amino acid Mtu recA intein consists of independent protein-splicing and endonuclease domains. Previously, removal of the central endonuclease domain of the intein, and selection for function, generated a 168-residue mini-intein, ΔI-SM, that had splicing activity similar to that of the full-l...

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Hlavní autoři: Van Roey, Patrick, Pereira, Brian, Li, Zhong, Hiraga, Kaori, Belfort, Marlene, Derbyshire, Victoria
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852430/
https://ncbi.nlm.nih.gov/pubmed/17254599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.12.050
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