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Cell-free production of scFv fusion proteins: an efficient approach for personalized lymphoma vaccines
The unique immunoglobulin (Ig) idiotype on the surface of each B-cell lymphoma represents an ideal tumor-specific antigen for use as a therapeutic vaccine. We have used an Escherichia coli—based, cell-free protein-expression system to produce a vaccine within hours of cloning the Ig genes from a B-c...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1852255/ https://ncbi.nlm.nih.gov/pubmed/17164345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-07-030593 |
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