Direct adhesion to bone marrow stroma via fibronectin receptors inhibits hematopoietic progenitor proliferation.

In long-term bone marrow cultures, stroma-adherent progenitors proliferate significantly less than nonadherent progenitors. Thus, close progenitor-stroma interactions may serve to regulate or restrict rather than promote hematopoietic progenitor proliferation. We hypothesized that signaling through...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Hurley, R W, McCarthy, J B, Verfaillie, C M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1995
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185225/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7542285/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118063
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