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Direct adhesion to bone marrow stroma via fibronectin receptors inhibits hematopoietic progenitor proliferation.

In long-term bone marrow cultures, stroma-adherent progenitors proliferate significantly less than nonadherent progenitors. Thus, close progenitor-stroma interactions may serve to regulate or restrict rather than promote hematopoietic progenitor proliferation. We hypothesized that signaling through...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Principais autores: Hurley, R W, McCarthy, J B, Verfaillie, C M
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 1995
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185225/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7542285/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118063
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