CD34 cells from patients with trisomy 8 myelodysplastic syndrome (MDS) express early apoptotic markers but avoid programmed cell death by up-regulation of antiapoptotic proteins

CD34 cells from patients with trisomy 8 myelodysplastic syndrome (MDS) are distinguished from other MDS cells and from normal hematopoietic cells by their pronounced expression of apoptotic markers. Paradoxically, trisomy 8 clones can persist in patients with bone marrow failure and expand following...

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Detalhes bibliográficos
Main Authors: Sloand, Elaine M., Pfannes, Loretta, Chen, Gubin, Shah, Simant, Solomou, Elena E., Barrett, John, Young, Neal S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2007
Assuntos:
Hematopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852203/
https://ncbi.nlm.nih.gov/pubmed/17090657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-01-030643
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