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Preferential suppression of trisomy 8 compared with normal hematopoietic cell growth by autologous lymphocytes in patients with trisomy 8 myelodysplastic syndrome

Clinical observations and experimental evidence link bone marrow failure in myelodysplastic syndrome (MDS) with a T cell–dominated autoimmune process. Immunosuppressive therapy is effective in improving cytopenias in selected patients. Trisomy 8 is a frequent cytogenetic abnormality in bone marrow c...

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Detalhes bibliográficos
Main Authors: Sloand, Elaine M., Mainwaring, Lori, Fuhrer, Monika, Ramkissoon, Shakti, Risitano, Antonio M., Keyvanafar, Keyvan, Lu, Jun, Basu, Atanu, Barrett, A. John, Young, Neal S.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895154/
https://ncbi.nlm.nih.gov/pubmed/15827127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-05-2017
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