Production and localization of 92-kilodalton gelatinase in abdominal aortic aneurysms. An elastolytic metalloproteinase expressed by aneurysm-infiltrating macrophages.

Abdominal aortic aneurysms (AAA) are characterized by disruption and degradation of the elastic media, yet the elastolytic proteinases involved and their cellular sources are undefined. We examined if 92-kD gelatinase, an elastolytic matrix metalloproteinase, participates in the pathobiology of AAA....

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Publié dans:	J Clin Invest
Auteurs principaux:	Thompson, R W, Holmes, D R, Mertens, R A, Liao, S, Botney, M D, Mecham, R P, Welgus, H G, Parks, W C
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 1995
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185203/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7615801/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118037
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