Expression of 92-kD type IV collagenase/gelatinase (gelatinase B) in osteoarthritic cartilage and its induction in normal human articular cartilage by interleukin 1.

We report here that a 92-kD gelatinolytic metalloproteinase is expressed as protein and mRNA in human osteoarthritic cartilage, but not in normal adult articular cartilage. Western immunoblotting demonstrated that the 92-kD gelatinolytic activity corresponded to 92-kD type IV collagenase/gelatinase...

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Bibliografiske detaljer
Main Authors: Mohtai, M, Smith, R L, Schurman, D J, Tsuji, Y, Torti, F M, Hutchinson, N I, Stetler-Stevenson, W G, Goldberg, G I
Format: Artigo
Sprog:Inglês
Udgivet: 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC293560/
https://ncbi.nlm.nih.gov/pubmed/8325982
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