Expression of 92-kD type IV collagenase/gelatinase (gelatinase B) in osteoarthritic cartilage and its induction in normal human articular cartilage by interleukin 1.

We report here that a 92-kD gelatinolytic metalloproteinase is expressed as protein and mRNA in human osteoarthritic cartilage, but not in normal adult articular cartilage. Western immunoblotting demonstrated that the 92-kD gelatinolytic activity corresponded to 92-kD type IV collagenase/gelatinase...

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Main Authors: Mohtai, M, Smith, R L, Schurman, D J, Tsuji, Y, Torti, F M, Hutchinson, N I, Stetler-Stevenson, W G, Goldberg, G I
Formato: Artigo
Idioma:Inglês
Publicado: 1993
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC293560/
https://ncbi.nlm.nih.gov/pubmed/8325982
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