Expression of 92-kD type IV collagenase/gelatinase (gelatinase B) in osteoarthritic cartilage and its induction in normal human articular cartilage by interleukin 1.

We report here that a 92-kD gelatinolytic metalloproteinase is expressed as protein and mRNA in human osteoarthritic cartilage, but not in normal adult articular cartilage. Western immunoblotting demonstrated that the 92-kD gelatinolytic activity corresponded to 92-kD type IV collagenase/gelatinase...

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Publicado en:	J Clin Invest
Autores principales:	Mohtai, M, Smith, R L, Schurman, D J, Tsuji, Y, Torti, F M, Hutchinson, N I, Stetler-Stevenson, W G, Goldberg, G I
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Clinical Investigation 1993
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC293560/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8325982/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116547
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