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Production and localization of 92-kilodalton gelatinase in abdominal aortic aneurysms. An elastolytic metalloproteinase expressed by aneurysm-infiltrating macrophages.

Abdominal aortic aneurysms (AAA) are characterized by disruption and degradation of the elastic media, yet the elastolytic proteinases involved and their cellular sources are undefined. We examined if 92-kD gelatinase, an elastolytic matrix metalloproteinase, participates in the pathobiology of AAA....

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Publicado en:J Clin Invest
Principais autores: Thompson, R W, Holmes, D R, Mertens, R A, Liao, S, Botney, M D, Mecham, R P, Welgus, H G, Parks, W C
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 1995
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185203/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7615801/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118037
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