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TREM2-Transduced Myeloid Precursors Mediate Nervous Tissue Debris Clearance and Facilitate Recovery in an Animal Model of Multiple Sclerosis

BACKGROUND: In multiple sclerosis, inflammation can successfully be prevented, while promoting repair is still a major challenge. Microglial cells, the resident phagocytes of the central nervous system (CNS), are hematopoietic-derived myeloid cells and express the triggering receptor expressed on my...

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Detalhes bibliográficos
Main Authors: Takahashi, Kazuya, Prinz, Marco, Stagi, Massimiliano, Chechneva, Olga, Neumann, Harald
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851623/
https://ncbi.nlm.nih.gov/pubmed/17425404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0040124
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