RAGE Drives the Development of Glomerulosclerosis and Implicates Podocyte Activation in the Pathogenesis of Diabetic Nephropathy

Diabetic nephropathy ensues from events involving earliest changes in the glomeruli and podocytes, followed by accumulation of extracellular matrix in the mesangium. Postulated mechanisms include roles for vascular endothelial growth factor (VEGF), produced by podocytes and contributing to enhanced...

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Autors principals: Wendt, Thoralf M., Tanji, Nozomu, Guo, Jiancheng, Kislinger, Thomas R., Qu, Wu, Lu, Yan, Bucciarelli, Loredana G., Rong, Ling Ling, Moser, Bernhard, Markowitz, Glen S., Stein, Gunther, Bierhaus, Angelika, Liliensiek, Birgit, Arnold, Bernd, Nawroth, Peter P., Stern, David M., D’Agati, Vivette D., Schmidt, Ann Marie
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2003
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851245/
https://ncbi.nlm.nih.gov/pubmed/12651605
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