RAGE Drives the Development of Glomerulosclerosis and Implicates Podocyte Activation in the Pathogenesis of Diabetic Nephropathy

Diabetic nephropathy ensues from events involving earliest changes in the glomeruli and podocytes, followed by accumulation of extracellular matrix in the mesangium. Postulated mechanisms include roles for vascular endothelial growth factor (VEGF), produced by podocytes and contributing to enhanced...

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Detalhes bibliográficos
Main Authors: Wendt, Thoralf M., Tanji, Nozomu, Guo, Jiancheng, Kislinger, Thomas R., Qu, Wu, Lu, Yan, Bucciarelli, Loredana G., Rong, Ling Ling, Moser, Bernhard, Markowitz, Glen S., Stein, Gunther, Bierhaus, Angelika, Liliensiek, Birgit, Arnold, Bernd, Nawroth, Peter P., Stern, David M., D’Agati, Vivette D., Schmidt, Ann Marie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2003
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851245/
https://ncbi.nlm.nih.gov/pubmed/12651605
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