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The major transition state in folding need not involve the immobilization of side chains

During protein folding in which few, if any, definable kinetic intermediates are observable, the nature of the transition state is central to understanding the course of the reaction. Current experimental data does not distinguish the relative contributions of side chain immobilization and dehydrati...

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Detalhes bibliográficos
Main Authors: Staniforth, Rosemary A., Dean, Jonathan L. E., Zhong, Qi, Zerovnik, Eva, Clarke, Anthony R., Waltho, Jonathan P.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC18512/
https://ncbi.nlm.nih.gov/pubmed/10823937
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