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Aberrant Expression and Activation of the Thrombin Receptor Protease-Activated Receptor-1 Induces Cell Proliferation and Motility in Human Colon Cancer Cells

The traditional view on the role of serine proteases in tumor biology has changed with the recent discovery of a family of protease-activated receptors (PARs). In this study we explored the expression and functional role of the thrombin receptor PAR-1 in human colon cancer cells. Reverse transcripta...

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Autors principals: Darmoul, Dalila, Gratio, Valérie, Devaud, Hélène, Lehy, Thérèse, Laburthe, Marc
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851194/
https://ncbi.nlm.nih.gov/pubmed/12707033
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