Kallikrein-Related Peptidase 14 Acts on Proteinase-Activated Receptor 2 to Induce Signaling Pathway in Colon Cancer Cells

Serine proteinases participate in tumor growth and invasion by cleaving and activating proteinase-activated receptors (PARs). Recent studies have implicated PAR-1 and PAR-4 (activated by thrombin) and PAR-2 (activated by trypsin but not by thrombin) in human colon cancer growth. The endogenous activ...

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Detalhes bibliográficos
Main Authors: Gratio, Valérie, Loriot, Céline, Virca, G. Duke, Oikonomopoulou, Katerina, Walker, Francine, Diamandis, Eleftherios P., Hollenberg, Morley D., Darmoul, Dalila
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204030/
https://ncbi.nlm.nih.gov/pubmed/21907696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.07.016
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