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The Origin of Phenotypic Heterogeneity in a Clonal Cell Population In Vitro

BACKGROUND: The spontaneous emergence of phenotypic heterogeneity in clonal populations of mammalian cells in vitro is a rule rather than an exception. We consider two simple, mutually non-exclusive models that explain the generation of diverse cell types in a homogeneous population. In the first mo...

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Bibliografische gegevens
Hoofdauteurs: Stockholm, Daniel, Benchaouir, Rachid, Picot, Julien, Rameau, Philippe, Neildez, Thi My Anh, Landini, Gabriel, Laplace-Builhé, Corinne, Paldi, Andras
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851097/
https://ncbi.nlm.nih.gov/pubmed/17460761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000394
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