Bistable Cell Fate Specification as a Result of Stochastic Fluctuations and Collective Spatial Cell Behaviour

BACKGROUND: In culture, isogenic mammalian cells typically display enduring phenotypic heterogeneity that arises from fluctuations of gene expression and other intracellular processes. This diversity is not just simple noise but has biological relevance by generating plasticity. Noise driven plastic...

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Detalles Bibliográficos
Autores principales: Stockholm, Daniel, Edom-Vovard, Frédérique, Coutant, Sophie, Sanatine, Peggy, Yamagata, Yoshiaki, Corre, Guillaume, Le Guillou, Laurent, Neildez-Nguyen, Thi My Anh, Pàldi, Andràs
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010982/
https://ncbi.nlm.nih.gov/pubmed/21203432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014441
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