Bistable Cell Fate Specification as a Result of Stochastic Fluctuations and Collective Spatial Cell Behaviour

BACKGROUND: In culture, isogenic mammalian cells typically display enduring phenotypic heterogeneity that arises from fluctuations of gene expression and other intracellular processes. This diversity is not just simple noise but has biological relevance by generating plasticity. Noise driven plastic...

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Detalhes bibliográficos
Main Authors: Stockholm, Daniel, Edom-Vovard, Frédérique, Coutant, Sophie, Sanatine, Peggy, Yamagata, Yoshiaki, Corre, Guillaume, Le Guillou, Laurent, Neildez-Nguyen, Thi My Anh, Pàldi, Andràs
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010982/
https://ncbi.nlm.nih.gov/pubmed/21203432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014441
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