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The Origin of Phenotypic Heterogeneity in a Clonal Cell Population In Vitro
BACKGROUND: The spontaneous emergence of phenotypic heterogeneity in clonal populations of mammalian cells in vitro is a rule rather than an exception. We consider two simple, mutually non-exclusive models that explain the generation of diverse cell types in a homogeneous population. In the first mo...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1851097/ https://ncbi.nlm.nih.gov/pubmed/17460761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000394 |
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