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Inviting Instability: Transposable elements, Double-strand breaks, and the Maintenance of Genome Integrity

The ubiquity of mobile elements in mammalian genomes poses considerable challenges for the maintenance of genome integrity. The predisposition of mobile elements towards participation in genomic rearrangements is largely a consequence of their interspersed homologous nature. As tracts of nonallelic...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hedges, D. J., Deininger, P. L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850990/
https://ncbi.nlm.nih.gov/pubmed/17157332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2006.11.021
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