Caricamento...

Age-Dependent Loss of Tolerance to an Immunodominant Epitope of Glutamic Acid Decarboxylase in Diabetic prone RIP-B7/DR4 Mice

We have identified for the first time an age-dependent spontaneous loss of tolerance to two self-antigenic epitopes derived from putative diabetes associated antigens glutamic acid decarboxylase (GAD65) and glial fibrillary acidic protein (GFAP) in RIP-B7/DRB1(*)0404 HLA transgenic mice. Diabetic an...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Gebe, John A., Unrath, Kellee A, Falk, Ben A., Ito, Kouichi, Wen, Li, Daniels, Terri L., Lernmark, Åke, Nepom, Gerald T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850983/
https://ncbi.nlm.nih.gov/pubmed/16979383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2006.08.002
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !