Induction of Colitis in Mice Deficient of Peyer’s Patches and Mesenteric Lymph Nodes Is Associated with Increased Disease Severity and Formation of Colonic Lymphoid Patches

Inflammatory bowel disease is associated with immune activation in Peyer’s patches and mucosal lymph nodes. The role of these organs in dextran sodium sulfate (DSS)-induced colitis was investigated. We used mice lacking Peyer’s patches and/or lymph nodes because of lymphotoxin-α gene deficiency or t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Spahn, Thomas W., Herbst, Hermann, Rennert, Paul D., Lügering, Norbert, Maaser, Christian, Kraft, Mathias, Fontana, Adriano, Weiner, Howard L., Domschke, Wolfram, Kucharzik, Torsten
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Investigative Pathology 2002
Gaiak:
Animal Models
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850913/
https://ncbi.nlm.nih.gov/pubmed/12466141
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