Absence of CCR6 Inhibits CD4(+) Regulatory T-Cell Development and M-Cell Formation inside Peyer’s Patches

The chemokine Mip3α is specifically expressed by the follicle-associated epithelia (FAE) covering intestinal Peyer’s patches (PPs) and is the only known chemokine ligand for the chemokine receptor CCR6. Although CCR6-deficient mice are known to have a perturbed intestinal immune system, little is kn...

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Bibliographische Detailangaben
Hauptverfasser: Lügering, Andreas, Floer, Martin, Westphal, Sabine, Maaser, Christian, Spahn, Thomas W., Alexander Schmidt, M., Domschke, Wolfram, Williams, Ifor R., Kucharzik, Torsten
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2005
Schlagworte:
Original Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602423/
https://ncbi.nlm.nih.gov/pubmed/15920150
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