Stat6-Deficient Mice Develop Airway Hyperresponsiveness and Peribronchial Fibrosis during Chronic Fungal Asthma

Signal transducer and activator of transcription 6 (Stat6) is critical for Th2-mediated responses during allergic airway disease. To investigate the role of Stat6 in fungus-induced airway hyperresponsiveness and remodeling, Stat6-deficient (Stat6−/−) and Stat6-wildtype (Stat6+/+) mice were sensitize...

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Main Authors: Blease, Kate, Schuh, Jane M., Jakubzick, Claudia, Lukacs, Nicholas W., Kunkel, Steven L., Joshi, Bharat H., Puri, Raj K., Kaplan, Mark H., Hogaboam, Cory M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2002
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Regular Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850665/
https://ncbi.nlm.nih.gov/pubmed/11839568
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