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Pivotal Role of Signal Transducer and Activator of Transcription (Stat)4 and Stat6 in the Innate Immune Response during Sepsis

Signal transducer and activator of transcription (Stat)4 and Stat6 are transcription factors that provide type 1 and type 2 response, respectively. Here, we explored the role of Stat4 and Stat6 in innate immunity during septic peritonitis. Stat4(−/)− and Stat6(−/)− mice were resistant to the lethali...

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Detalhes bibliográficos
Main Authors: Matsukawa, Akihiro, Kaplan, Mark H., Hogaboam, Cory M., Lukacs, Nicholas W., Kunkel, Steven L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193416/
https://ncbi.nlm.nih.gov/pubmed/11257135
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