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Mitochondrial Toxin 3-Nitropropionic Acid Induces Cardiac and Neurotoxicity Differentially in Mice

We investigated the effects of 3-nitropropionic acid (3NPA), a previously characterized neurotoxin, in four strains of mice to better understand the molecular basis of variable host responses to this agent. Unexpectedly, we found significant cardiac toxicity that always accompanied the neurotoxicity...

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Autori principali: Gabrielson, Kathleen L., Hogue, Barbara A., Bohr, Vilhelm A., Cardounel, A. J., Nakajima, Waco, Kofler, Julia, Zweier, Jay L., Rodriguez, E. Rene, Martin, Lee J., de Souza-Pinto, Nadja C., Bressler, Joseph
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850498/
https://ncbi.nlm.nih.gov/pubmed/11583977
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