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Increased Expression of Osteopontin in the Degenerating Striatum of Rats Treated with Mitochondrial Toxin 3-Nitropropionic Acid: A Light and Electron Microscopy Study

The mycotoxin 3-nitropropionic acid (3NP) is an irreversible inhibitor that induces neuronal damage by inhibiting mitochondrial complex II. Neurodegeneration induced by 3NP, which is preferentially induced in the striatum, is caused by an excess influx and accumulation of calcium in mitochondria. Os...

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Detalhes bibliográficos
Publicado no:Acta Histochem Cytochem
Main Authors: Kim, Hong-Lim, Lee, Mun-Yong, Shin, Yoo-Jin, Song, Doo-Won, Park, Jieun, Chang, Byung-Soo, Lee, Jong-Hwan
Formato: Artigo
Idioma:Inglês
Publicado em: JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652028/
https://ncbi.nlm.nih.gov/pubmed/26633905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1267/ahc.15010
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