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Mechanical Tension Controls Granulation Tissue Contractile Activity and Myofibroblast Differentiation

We have examined the role of mechanical tension in myofibroblast differentiation using two in vivo rat models. In the first model, granulation tissue was subjected to an increase in mechanical tension by splinting a full-thickness wound with a plastic frame. Myofibroblast features, such as stress fi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hinz, Boris, Mastrangelo, Dominique, Iselin, Christophe E., Chaponnier, Christine, Gabbiani, Giulio
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2001
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850455/
https://ncbi.nlm.nih.gov/pubmed/11549593
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