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Mechanical Tension Controls Granulation Tissue Contractile Activity and Myofibroblast Differentiation

We have examined the role of mechanical tension in myofibroblast differentiation using two in vivo rat models. In the first model, granulation tissue was subjected to an increase in mechanical tension by splinting a full-thickness wound with a plastic frame. Myofibroblast features, such as stress fi...

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Autors principals: Hinz, Boris, Mastrangelo, Dominique, Iselin, Christophe E., Chaponnier, Christine, Gabbiani, Giulio
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850455/
https://ncbi.nlm.nih.gov/pubmed/11549593
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