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Mechanical Tension Controls Granulation Tissue Contractile Activity and Myofibroblast Differentiation

We have examined the role of mechanical tension in myofibroblast differentiation using two in vivo rat models. In the first model, granulation tissue was subjected to an increase in mechanical tension by splinting a full-thickness wound with a plastic frame. Myofibroblast features, such as stress fi...

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Main Authors: Hinz, Boris, Mastrangelo, Dominique, Iselin, Christophe E., Chaponnier, Christine, Gabbiani, Giulio
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2001
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850455/
https://ncbi.nlm.nih.gov/pubmed/11549593
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