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High Glucose-Induced Hypertrophy of Mesangial Cells Requires p27(Kip1), an Inhibitor of Cyclin-Dependent Kinases
Hypertrophy of mesangial cells is one of the earliest morphological alterations in the kidney after the onset of diabetes mellitus. We have previously shown that cultured mesangial cells exposed to high ambient glucose arrest in the G(1) phase of the cell cycle and that this is associated with an in...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Investigative Pathology
2001
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1850372/ https://ncbi.nlm.nih.gov/pubmed/11238057 |
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