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Mycophenolate mofetil and roscovitine decrease cyclin expression and increase p27(kip1) expression in anti Thy1 mesangial proliferative nephritis

The response of mesangial cells to a phlogistic challenge includes cell proliferation and mesangial matrix expansion. Cell proliferation is a highly regulated process which includes enhancing factors such as cyclins, cyclin dependent kinases, and inhibitory proteins, such as p27(kip1). The aim of th...

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Hlavní autoři: Chiara, M, Menegatti, E, Di Simone, D, Davit, A, Bellis, D, Sferch, D, De Rosa, G, Giachino, O, Sena, L M, Roccatello, D
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809292/
https://ncbi.nlm.nih.gov/pubmed/15654821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2004.02684.x
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