Inhibition of Type I Procollagen Synthesis by Damaged Collagen in Photoaged Skin and by Collagenase-Degraded Collagen in Vitro

Type I and type III procollagen are reduced in photodamaged human skin. This reduction could result from increased degradation by metalloproteinases and/or from reduced procollagen synthesis. In the present study, we investigated type I procollagen production in photodamaged and sun-protected human...

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Main Authors: Varani, James, Spearman, Dara, Perone, Patricia, Fligiel, Suzanne E. G., Datta, Subhash C., Wang, Zeng Quan, Shao, Yuan, Kang, Sewon, Fisher, Gary J., Voorhees, John J.
格式: Artigo
語言:Inglês
出版: American Society for Investigative Pathology 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850364/
https://ncbi.nlm.nih.gov/pubmed/11238041
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