Macrophage Myeloperoxidase Regulation by Granulocyte Macrophage Colony-Stimulating Factor in Human Atherosclerosis and Implications in Acute Coronary Syndromes

Inflammation and oxidative stress contribute to the pathogenesis of many human diseases including atherosclerosis. Advanced human atheroma contains high levels of the enzyme myeloperoxidase that produces the pro-oxidant species, hypochlorous acid (HOCl). This study documents increased numbers of mye...

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Detalhes bibliográficos
Main Authors: Sugiyama, Seigo, Okada, Yoshikatsu, Sukhova, Galina K., Virmani, Renu, Heinecke, Jay W., Libby, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2001
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850342/
https://ncbi.nlm.nih.gov/pubmed/11238037
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