Macrophage Myeloperoxidase Regulation by Granulocyte Macrophage Colony-Stimulating Factor in Human Atherosclerosis and Implications in Acute Coronary Syndromes

Inflammation and oxidative stress contribute to the pathogenesis of many human diseases including atherosclerosis. Advanced human atheroma contains high levels of the enzyme myeloperoxidase that produces the pro-oxidant species, hypochlorous acid (HOCl). This study documents increased numbers of mye...

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Библиографические подробности
Главные авторы: Sugiyama, Seigo, Okada, Yoshikatsu, Sukhova, Galina K., Virmani, Renu, Heinecke, Jay W., Libby, Peter
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Investigative Pathology 2001
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Regular Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850342/
https://ncbi.nlm.nih.gov/pubmed/11238037
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