Oxidative Stress and Induction of Heme Oxygenase-1 in the Kidney in Sickle Cell Disease

Chronic nephropathy is a recognized complication of sickle cell disease. Using a transgenic sickle mouse, we examined whether oxidative stress occurs in the sickle kidney, the origins and functional significance of such oxidant stress, and the expression of the oxidant-inducible, potentially protect...

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Bibliographic Details
Main Authors: Nath, Karl A., Grande, Joseph P., Haggard, Jill J., Croatt, Anthony J., Katusic, Zvonimir S., Solovey, Anna, Hebbel, Robert P.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2001
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850341/
https://ncbi.nlm.nih.gov/pubmed/11238038
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